01
Ipamorelin, the first selective growth hormone secretagogue
Original characterization of Ipamorelin selectivity in rodent and swine pituitary cell preparations.
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Peptides · CAS 170851-70-4 ≥99% Purity · HPLC verified
Ipamorelin 10MG
Research-grade Ipamorelin peptide. ≥99% purity, third-party verified via HPLC. For research and laboratory use only.
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Identity
Compound information
What is Ipamorelin?
Ipamorelin is a synthetic pentapeptide growth hormone secretagogue first developed by Novo Nordisk in 1998. It is a selective agonist of the ghrelin/GHS-R1a receptor, studied for its release of growth hormone in pituitary cell preparations without significant cortisol or prolactin elevation.
CAS Number 170851-70-4
Molecular Formula C38H49N9O5
Molecular Weight 711.86 g/mol
Amino Acid Sequence Aib-His-D-2-Nal-D-Phe-Lys-NH₂
Half-Life ~2 hours (intravenous, rat models)
Source Synthetic peptide
Purity 99.5% (HPLC verified)
Form Lyophilized powder
Solubility Soluble in water, bacteriostatic water
Storage
Stability information
Long-term
−20°C
Lyophilized powder, sealed
Reconstituted
2–8°C
Up to 30 days when refrigerated
Shipping
Room temp
Stable in transit, lyophilized
Protection
Light · Moisture
Store sealed, away from light
Background
About this compound
Ipamorelin is a pentapeptide and selective ghrelin receptor (GHS-R) agonist, studied for its role in growth hormone secretagogue pathways. Known for selectivity over other endocrine axes in laboratory models. Each vial contains 10mg lyophilized powder at ≥99% purity.
Specifications:
- Purity: ≥99% (HPLC verified)
- Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2
- Form: Lyophilized powder
- Storage: -20°C (long-term), 2-8°C (reconstituted)
- Certificate of Analysis available
For research and laboratory use only. Not for human consumption.
Bibliography
Sources & references
02
The growth hormone secretagogue receptor: its intracellular signaling and regulation
Review of GHS-R1a signaling pathways relevant to ghrelin receptor agonists.
View source →03
Ghrelin: structure and function
Foundational review of ghrelin/GHS-R receptor pharmacology.
View source →04
Comparison of ipamorelin with growth hormone-releasing peptide-6 on growth hormone secretion
Comparative GH secretion study in rodent and swine models.
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