01
Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295
Pharmacodynamic study of CJC-1295 GHRH analog in healthy adult subjects.
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Peptides · CAS 863288-34-0 ≥99% Purity · HPLC verified
CJC-1295 No DAC 5MG
Research-grade CJC-1295 (No DAC) peptide. ≥99% purity, third-party verified via HPLC. For research and laboratory use only.
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Frequently researched together
Identity
Compound information
What is CJC-1295 (No DAC)?
CJC-1295 (No DAC), also known as Modified GRF (1-29) or Mod-GRF, is a synthetic 30 amino acid peptide analog of growth hormone-releasing hormone (GHRH). The "No DAC" designation indicates the absence of the Drug Affinity Complex (a maleimide that binds albumin), giving this version a short serum half-life.
Studied in laboratory settings for GHRH receptor binding kinetics and pulsatile growth hormone release in pituitary preparations.
CAS Number 863288-34-0
Molecular Formula C152H252N44O42
Molecular Weight 3367.97 g/mol
Amino Acid Sequence Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH₂
Half-Life ~30 minutes
Source Synthetic peptide
Purity 99.3% (HPLC verified)
Form Lyophilized powder
Solubility Soluble in water, bacteriostatic water
Storage
Stability information
Long-term
−20°C
Lyophilized powder, sealed
Reconstituted
2–8°C
Up to 30 days when refrigerated
Shipping
Room temp
Stable in transit, lyophilized
Protection
Light · Moisture
Store sealed, away from light
Background
About this compound
CJC-1295 without DAC (also known as Modified GRF 1-29) is a 30-amino-acid synthetic analog of growth hormone-releasing hormone (GHRH). The non-DAC variant has a short half-life and is commonly studied alongside ghrelin mimetics. Each vial contains 5mg lyophilized powder at ≥99% purity.
Specifications:
- Purity: ≥99% (HPLC verified)
- Form: Lyophilized powder
- Storage: -20°C (long-term), 2-8°C (reconstituted)
- Certificate of Analysis available
For research and laboratory use only. Not for human consumption.
Bibliography
Sources & references
02
Sustained growth hormone-releasing hormone receptor activation
Review of GHRH analog pharmacology including CJC-1295 mechanism.
View source →03
Growth hormone-releasing hormone (GHRH) and its analogs
Comprehensive review of GHRH receptor pharmacology and synthetic analogs.
View source →04
Growth hormone secretagogues: history, mechanism of action, and clinical development
Review covering both GHRH analogs and ghrelin agonists in research literature.
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