01
Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295
Pharmacodynamic and pharmacokinetic profile of DAC-modified CJC-1295 in adults.
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Peptides · CAS 863288-34-0 ≥99% Purity · HPLC verified
CJC-1295 with DAC 5MG
Research-grade CJC-1295 with DAC peptide. ≥99% purity, third-party verified via HPLC. For research and laboratory use only.
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Identity
Compound information
What is CJC-1295 with DAC?
CJC-1295 with DAC is a synthetic 30 amino acid GHRH analog modified with a Drug Affinity Complex (DAC) — a maleimide group that covalently bonds to serum albumin. This albumin conjugation extends the half-life dramatically compared to the No-DAC version, producing sustained elevation of growth hormone and IGF-1 in research models.
CAS Number 863288-34-0
Molecular Formula C165H269N47O46
Molecular Weight 3647.20 g/mol
Amino Acid Sequence Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys(MPA)-NH₂
Half-Life ~6–8 days
Source Synthetic peptide with DAC modification
Purity 99.2% (HPLC verified)
Form Lyophilized powder
Solubility Soluble in water, bacteriostatic water
Storage
Stability information
Long-term
−20°C
Lyophilized powder, sealed
Reconstituted
2–8°C
Up to 30 days when refrigerated
Shipping
Room temp
Stable in transit, lyophilized
Protection
Light · Moisture
Store sealed, away from light
Background
About this compound
CJC-1295 with DAC is a synthetic GHRH analog modified with a Drug Affinity Complex (DAC), extending its plasma half-life through albumin binding. Studied in laboratory settings for its prolonged signaling profile compared to non-DAC variants. Each vial contains 5mg lyophilized powder at ≥99% purity.
Specifications:
- Purity: ≥99% (HPLC verified)
- Form: Lyophilized powder
- Storage: -20°C (long-term), 2-8°C (reconstituted)
- Certificate of Analysis available
For research and laboratory use only. Not for human consumption.
Bibliography
Sources & references
02
Drug Affinity Complex (DAC) extension of peptide half-life via covalent albumin binding
Foundational paper on DAC technology used in CJC-1295.
View source →03
GHRH analogs: pharmacology and clinical research applications
Review of long-acting GHRH analogs including CJC-1295.
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