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Metabolic · Research grade ✓ ≥99.0% PURITY

5-Amino-1MQ 5MG 5 mg

What is 5-Amino-1MQ? 5-Amino-1MQ is a small-molecule quinolinium derivative studied in laboratory models as a selective, membrane-permeable inhibitor of nicotinamide N-methyltransferase (NNMT). NNMT sits at the intersection of cellular methylation and NAD+ salvage pathways, and its inhibition has be...

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HPLC + MS verified Same-day dispatch before 2 PM ET CoA by lot number
Purity
99.0%
Form
LYO
Identity
MS ✓
Specification +
Compound5-Amino-1MQ 5MG
Half-lifeNot fully characterized (rodent PK studies)
Purity (HPLC)≥ 99.0%
Testing & CoA +
Every lot passes a four-method release protocol — RP-HPLC purity (220nm), LC-MS identity, LAL endotoxin screen (<0.5 EU/mg), and Karl Fischer residual moisture. The batch-matched Certificate of Analysis ships in the box and is retrievable by lot number.
Research library (3) +
Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice Neelakantan H, Vance V, Wetzel MD, et al. · Biochemical Pharmacology · 2018 · DOI
Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle Neelakantan H, Brightwell CR, Graber TG, et al. · Biochemical Pharmacology · 2019 · DOI
Nicotinamide N-methyltransferase: more than a vitamin B3 clearance enzyme Pissios P · Trends in Endocrinology & Metabolism · 2017 · DOI
Storage & handling +
Store lyophilized at −20 °C, desiccated and protected from light. Reconstitute with bacteriostatic or sterile water. For research and laboratory use only — not for human or veterinary use.
Shipping & returns +
Orders before 2 PM ET dispatch the same business day from our U.S. facility. Free shipping over $250. Full reshipment coverage on lost or damaged parcels.
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5-Amino-1MQ 5MG

$35.00

Research-grade 5-Amino-1MQ (5-amino-1-methylquinolinium), a small-molecule NNMT inhibitor. ≥99% purity, third-party verified via HPLC. For research and laboratory use only.

SKU: LTF-AM-5 Category:

Description

5-Amino-1MQ (5-amino-1-methylquinolinium) is a membrane-permeable small molecule studied in laboratory settings as a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in cellular NAD+ and methylation balance. Each vial contains 5mg at ≥99% purity.

Specifications:

  • Purity: ≥99% (HPLC verified)
  • Form: Lyophilized powder
  • Storage: -20°C (long-term), 2-8°C (reconstituted)
  • Certificate of Analysis available

For research and laboratory use only. Not for human or veterinary use.

Additional information

Cas Number

42464-96-0

Molecular Formula

C10H11N2⁺ (cation)

Molecular Weight

159.21 g/mol (cation)

Composition

5-Amino-1-methylquinolinium (small-molecule NNMT inhibitor)

Solubility

Soluble in water, DMSO

Total Content

5 mg