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PEPTIDE
Semax Heptapeptide
$59Semax is a synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10) with a C-terminal Pro-Gly-Pro stabilizing sequence. Developed at the Institute of Molecular Genetics of the Russian Academy of Sciences alongside Selank, it has been studied for neurotrophic and neuroprotective properties in preclinical models.
Derived from ACTH(4-10) with modifications eliminating corticotropic activity while retaining neurotrophic signaling properties.
Investigated for effects on BDNF, NGF, and GDNF expression in neuronal cell culture and animal model research.
Interacts with MC3 and MC4 melanocortin receptors, enabling study of melanocortin signaling in neuroscience research.
Dolotov OV, et al. — Journal of Neurochemistry, 2006
Study demonstrating Semax's upregulation of BDNF and trkB receptor expression in hippocampal tissue models.
| Product Name | Semax |
| CAS Number | 80714-61-0 |
| Molecular Formula | C₃₇H₅₁N₉O₁₀S |
| Molecular Weight | 813.93 Da |
| Sequence | Met-Glu-His-Phe-Pro-Gly-Pro |
| Purity | ≥99% (HPLC) |
| Physical Form | White Lyophilized Powder |
| Storage | -20°C, protected from light |
| Certification | Third-party HPLC & MS verified |
| Intended Use | Research and laboratory use only |
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