01
The GPR54 gene as a regulator of puberty
Foundational paper identifying KISS1R signaling in pubertal development.
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Peptides · CAS 374675-21-5 ≥99% Purity · HPLC verified
Kisspeptin
Research-grade Kisspeptin-10 peptide. ≥99% purity, third-party verified via HPLC. For research and laboratory use only.
Dosage
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Identity
Compound information
What is Kisspeptin-10?
Kisspeptin-10 is the C-terminal decapeptide fragment of the KISS1 gene product (originally named metastin). It functions as the endogenous ligand at the GPR54 (KISS1R) receptor and has been studied extensively in laboratory settings for its role as an upstream regulator of the hypothalamic-pituitary-gonadal (HPG) axis.
CAS Number 374675-21-5
Molecular Formula C63H83N17O14
Molecular Weight 1302.46 g/mol
Amino Acid Sequence Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂
Half-Life ~4 minutes (intravenous, human plasma)
Source Synthetic peptide
Purity 99.5% (HPLC verified)
Form Lyophilized powder
Solubility Soluble in water, bacteriostatic water
Storage
Stability information
Long-term
−20°C
Lyophilized powder, sealed
Reconstituted
2–8°C
Up to 30 days when refrigerated
Shipping
Room temp
Stable in transit, lyophilized
Protection
Light · Moisture
Store sealed, away from light
Background
About this compound
Kisspeptin-10 is a decapeptide fragment of the KISS1 gene product, acting as an endogenous ligand at the GPR54 (KISS1R) receptor. Studied extensively in laboratory settings for its role in upstream regulation of the hypothalamic-pituitary-gonadal axis. Each vial contains lyophilized powder at ≥99% purity.
Specifications:
- Purity: ≥99% (HPLC verified)
- Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
- Form: Lyophilized powder
- Storage: -20°C (long-term), 2-8°C (reconstituted)
- Certificate of Analysis available
For research and laboratory use only. Not for human consumption.
Bibliography
Sources & references
02
Kisspeptin and the regulation of the reproductive axis
Comprehensive review of kisspeptin signaling in reproductive endocrinology.
View source →03
Kisspeptin signalling in the brain
Review of kisspeptin/GPR54 neuronal pathways in murine models.
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